At Navya Chem Pharma LLC, we specialize in the design and synthesis of Novel Chemical Entities (NCEs) and scaffolds to accelerate drug discovery and development. Our team combines medicinal chemistry expertise, innovative synthetic strategies, and advanced infrastructure to deliver unique chemical matter that drives lead identification and optimization.
We provide customized solutions for hit generation, lead expansion, and structure–activity relationship (SAR) studies, ensuring that each scaffold or NCE is synthetically accessible, chemically diverse, and biologically relevant.
Our Capabilities Include:
- Design and synthesis of novel scaffolds and NCEs
- Scaffold hopping and bioisostere design
- Focused and diverse compound sets for SAR studies
- Route scouting, optimization, and scale-up
- Full analytical and structural characterization
- Milligram to multi-gram scale deliveries
Why Choose Us?
With a strong foundation in innovative chemistry and problem-solving, Navya Chem Pharma delivers high-quality NCEs and scaffolds that enable pharmaceutical and biotech companies to expand their chemical space and accelerate discovery pipelines. Our scientific rigor, flexibility, and client-focused approach make us a reliable partner in early-stage drug discovery.
What Are NCEs and Scaffolds?
- Novel Chemical Entities (NCEs): Newly designed molecules with unique structures, offering potential as new drug candidates.
- Scaffolds: Core chemical backbones that serve as starting points for building libraries and analogues, helping researchers explore biological activity and optimize potency.
Together, NCEs and scaffolds form the foundation of modern drug discovery, supporting both small-molecule innovation and targeted therapies.
Applications of Our NCEs & Scaffolds Services
- Early drug discovery – hit generation and validation
- Lead optimization – exploration of SAR and analogues
- Library design – scaffold-based focused or diverse libraries
- Fragment-based drug discovery (FBDD) – small fragments for screening
- Patentable chemical matter – novel scaffolds for competitive IP
Partner With Navya Chem Pharma
By integrating creativity in molecular design, excellence in synthetic chemistry, and deep regulatory insight, Navya Chem Pharma helps clients discover new chemical matter that forms the backbone of next-generation therapies.